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                  治疗痛风的首选用药——非布司他片
                  日期:2015-09-11 | 浏览量:177
                      成都蓉药集团四川峨嵋山药业股份有限公司研发的治疗高尿酸血症3类新药非布司他,历时3年终于完成人体临床试验,于今年6?#30053;?#26149;城昆明召开临床总结会,揭盲数据显示非布司他片临床试验结果符合预期,在疗效和安全性方面均优于现行主流药物-别嘌醇片。标志着峨嵋山药业又一重磅产品——非布司他片临床试验取得了圆满成功。
                      
                  在非布司他上市之前,别嘌醇一直是临?#37319;?#21807;一用于抑制尿酸生成的药物。虽是经典老药,但由于自身结构缺陷,使用剂量大,副作用?#29616;亍?#38750;布司他是40年来首个获准治疗伴有高尿酸血症痛风的新药,主要用于伴有痛风症状的高尿酸血症患者的长期治疗。相比别嘌醇等其他治疗的药物,本品服用方便(每天只口服一次),?#30340;?#37240;效果更强,安全性更好,对肾损害患者还有?#27426;?#20462;复作用。
                      
                  本品最早于2009 年在美国上市,自上市以来保持较快增长势头。2012 年本品被《美国高尿酸血症痛风诊疗指南》推荐为首选?#30340;?#37240;药物,市场潜力巨大。
                      
                  据《中国药物应用与监测》统计,目前国内高尿酸血症患者的发病率为10%,即约有1.3 亿的潜在患者,并?#19968;?#32773;需要长期甚至终身服用?#30340;?#37240;药物,而现有药物临床治疗效果并不理想,因此非布司他国产化必将造福广大患者。
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